You Won't Believe What These Scientists Are Using AI For!

✨ CCMB and Aganitha join forces to apply Generative AI for therapeutic design and research

✨ Collaboration aims to accelerate drug discovery for diseases like malaria, TB, and neurological disorders

✨ Leveraging AI to predict, test, and optimize potential therapeutic compounds and nanobodies ✨ A step towards translating academic research into real-life solution.

• Who: Centre for Cellular and Molecular Biology (CCMB) and Aganitha

• What: Signed a framework agreement to apply Generative AI solutions for designing novel therapeutics and research tools

• When: Agreement signed on Wednesday, May 29, 2024

• Where: Hyderabad, India

• Why: To translate CCMB's R&D findings into therapeutic candidates by leveraging Aganitha's Generative AI capabilities

Imagine a world where artificial intelligence plays a pivotal role in designing life-saving therapies and propelling groundbreaking research. Well, that future is now, thanks to the genius minds at CCMB and Aganitha. Brace yourselves, because what they're up to will leave you awestruck! 🚀

In a bold and innovative move, the brilliant scientists at the Centre for Cellular and Molecular Biology (CCMB) a part of the Council of Scientific & Industrial Research (CSIR) and Aganitha which combines the power of deep science and deep tech to bring novel medicines to market faster, signed an umbrella memorandum of understanding (MoU) and Aganitha’s Generative AI solutions for small molecule and antibody design for translation of CCMB’s R&D findings into therapeutic candidates.

• Target analysis,

• Small molecule design, and

• Antibody and nanobody engineering

💊💻 This dynamic duo is on a mission to revolutionize the way we approach healthcare, and their secret weapon? Cutting-edge Generative AI technology that can generate novel ideas, solutions, and hypotheses at lightning speed. 💡

Imagine having an AI assistant that can sift through vast amounts of data, identify patterns, and propose groundbreaking therapeutic approaches – all while you sip your morning coffee. No more tedious trial-and-error processes or endless hours of manual research. 🕰️

When we continue to struggle with controlling malaria due to drug resistance of the pathogen, lack of broadly available vaccines, and insecticide resistance of mosquitoes.

Collaborative efforts of interdisciplinary experts are necessary to develop new drugs and vaccines for malaria. Towards this goal, they are leveraging Aganitha’s Generative AI capabilities in small molecules space for validated parasite drug targets to predict, test, and optimize potential antimalarial compounds," said Dr Puran Singh Sijwali, Senior Principal Scientist at CCMB.

But wait, there's more! This AI powerhouse doesn't just stop at drug design. It's also lending a helping hand in exploring uncharted territories of scientific inquiry, pushing the boundaries of what we thought was possible. 🔬

• Dr. Puran Singh Sijwali, Senior Principal Scientist at CCMB, shared their plan to leverage Aganitha's Generative AI capabilities to predict, test, and optimize potential antimalarial compounds, addressing the challenge of drug resistance.

• Dr. Raghunand Tirumalai, another Senior Principal Scientist at CCMB, expressed excitement about working on structure-based discovery of small molecule inhibitors targeting essential proteins of Mycobacterium tuberculosis, with the aim of identifying novel anti-TB therapeutic leads.

• Dr. Janesh Kumar, Senior Principal Scientist at CCMB, highlighted their collaboration with Aganitha to develop nanobody binders targeting GluD1 receptors, potentially unlocking new therapeutic avenues for neurological disorders like Alzheimer's and epilepsy.

With Generative AI on their side, CCMB and Aganitha are poised to unlock game-changing discoveries that could potentially save countless lives. Talk about being at the forefront of innovation! 🏆

As if that wasn't impressive enough, this collaboration is a testament to the power of teamwork and the pursuit of knowledge. By combining their expertise in biology, chemistry, and cutting-edge AI, they're setting a shining example of what can be achieved when brilliant minds come together. 🤝

CCMB Director Dr. Vinay Nandicoori lauded the collaboration as a timely move to take their lab leads towards more real-life solutions, leveraging CCMB's strength in fundamental disease biology research and Aganitha's expertise in AI-driven solutions.

Prasad Chodavarapu, co-founder and MD of Aganitha, sees this relationship as a great example of the academia-industry collaboration needed to make a significant impact towards solving human diseases and suffering.

So, buckle up, folks, because the future of medicine and research is here, and it's being shaped by the unstoppable force that is Generative AI.

Who knows what incredible breakthroughs await us? One thing's for sure – the world is about to witness a revolution like never before. 🌍✨

Mind you can use the prompts in most of the AI Design App like DALL E 3, Leonardo AI etc.

Sleek and sophisticated Instagram Reels storyboard for fashion/beauty magazine, minimalist design with neutral backdrop, multiple sectioned panels bordered by thin lines, soft textures like velvet and silk with pops of glitter, geometric shapes structuring space in an artful layout, optimized 3:4 aspect ratio, raw stylized rendering at 200

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An adorable corgi pup splashing joyfully in a pool, tongue lolling out with a happy doggy grin, playful iPhone wallpaper composition optimized for 3:4 aspect ratio, raw unfiltered photo-realism

Comical anthropomorphic snail creature curling huge iron dumbbell weights, displaying exaggerated chiseled muscles like a Mr. Olympia champion, dramatic cinematic lighting, hyper-realistic raw texture details, stylization 200

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Studio shot of a pink Porsche 930 turbo on a pink background, focal lens by 50mm, fujifilm, fine art, professional color grading (Gemini) 

An open newspaper with pages carved into the shape of waves, a person surfing on the waves, three-dimensional effect ar 3:4 style raw stylize 200

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As a reader of this newsletter, you can be part of this groundbreaking revolution in healthcare and scientific research. Here's what you can do:

✔️ Stay informed about the latest advancements in Generative AI and its applications in the medical field by following reputable sources and subscribing to relevant newsletters.

✔️ Support initiatives and organizations that promote collaboration between academia and industry, as these partnerships drive innovation and accelerate the translation of research into practical solutions.

✔️ Advocate for increased funding and resources for cutting-edge research projects that leverage AI and other emerging technologies to tackle pressing health challenges.

✔️ Encourage open dialogue and knowledge-sharing among experts from diverse fields, as interdisciplinary collaboration is key to unlocking the full potential of Generative AI in healthcare.

✔️ Embrace a growth mindset and remain curious about the possibilities that AI can bring to improving human lives and advancing scientific understanding.

By taking these actions, you can contribute to a future where Generative AI plays a pivotal role in designing life-saving therapies, accelerating drug discovery, and pushing the boundaries of what we thought was possible in medicine and research.

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3. Regard: Automates clinical tasks, allowing healthcare providers to allocate more time to patient care.

4. Twill: Integrates mental and physical healthcare solutions, employing AI for improved patient engagement and care plans.

5. Paige: Transforms cancer diagnosis and treatment with advanced AI in digital pathology.

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Sujata Padhy
Gen. AI Explorer